Application closing date 13/11/2019  
Salary £33,797 per annum  
Job category/type Research
Attachments  

Job description

Queen's University Belfast is one of the leading universities in the UK and Ireland and is a member of the Russell Group of UK research-intensive universities. Queen's combines excellence in research and education with a student centred ethos.  We have over 24,000 students, 4,200 staff and an annual turnover of some GBP 300m. We offer generous terms and conditions of employment underpinned by excellent benefits including attractive well-being, family friendly and other lifestyle benefits. Research staff at QUB are also entitled to up to 10 days per year to spend on activities benefiting their career development.  

Our five core values - Integrity, Connected, Ambition, Respect, Excellence - are shared by our staff and students, representing the expectations we have for ourselves and each other, guiding our day-to-day decisions and the way we behave as individuals in an international organisation. 

The Wellcome Wolfson Institute for Experimental Medicine (WWIEM) is an interdisciplinary research centre which is committed to the highest quality scientific endeavour, with over 250 basic and clinical scientists working on site. Our mission is to understand the mechanisms of disease and use that understanding to develop innovative new treatments and therapies to improve patient outcomes. 

We are recruiting for a Research Fellow to be a highly productive, ambitious and collaborative member of the Gremlin biology group led by Dr. Derek Brazil at the WWIEM. The position will involve working as part of an Invest Northern Ireland-funded Proof of Concept (POC) research programme that seeks to develop novel small molecule inhibitors of Gremlin1, a secreted antagonist of bone morphogenetic proteins (BMPs). These inhibitors have been identified in a high throughput drug screen and will now be optimised using medical chemistry approaches, as well as a range of cell biology assays to determine efficacy and potency. The outputs from this project will be the development of first and best in class lead Grem1 inhibitors that can be tested in pre-clinical models of colorectal cancer and kidney fibrosis. 

The project will utilise high throughput methods, single cell level approaches, and is based in a highly collaborative team, carrying out basic research. The post is a senior role in the team and as such, successful applicants will have responsibilities in independent research, supervision, planning, day-to-day lab management, collaborations and outreach. 

The successful candidate must: 

• Have or about to receive a PhD in Molecular Cell Biology, Pharmacology or a closely related area.
• At least 3 years recent research experience to include experience in molecular cell biology, Pharmacology or related subject.

This post is available for 12 months.

Informal enquiries may be directed to Dr Eric Campbell via email: E.Campbell@qub.ac.uk

Candidate Information
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