The post is funded by the Wellcome Trust to investigate the regulation of contraction in the heart. We recently discovered a new class of regulatory mechanism that mediates the fast autoregulatory responses of the heart, and this project aims to discover how those mechanisms work on the timescale of the heartbeat. We expect the results to be transformative for understanding the regulation of the healthy heart and for development of new therapies for heart disease. The post-holder will be primarily responsible for developing novel instrumentation and software for the proposed experiments, will join an experimental team at synchrotron X-ray facilities, conduct biophysical experiments on isolated heart tissue, and carry out quantitative analysis of X-ray diffraction and biophysical data.
The successful candidate is likely to have a PhD in the physical computer science or a quantitative aspect of biology, combining strong analytical skills with an interest in biomedicine and the ambition to develop a career in research at the interface between the physical and biomedical sciences. Training in the relevant methods will be provided.
This post will be offered on a fixed-term contract for 5 years.
This is a full-time post - 100% full time equivalent
The selection process will include a panel interview.