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Senior Research Associate - Biomedical and Life Sciences

Employer
LANCASTER UNIVERSITY
Location
Lancaster, Lancashire
Salary
£34,804 to £40,322
Closing date
27 Nov 2019

Job Details

Ref: A2840

Job title: Senior Research Associate

Department: Biomedical and Life Sciences

Salary range: £34,804 to £40,322

Closing Date: Wednesday 27 November 2019

Contract: Temporary

Job URL: https://hr-jobs.lancs.ac.uk/Vacancy.aspx?ref=A2840

We are looking for a postdoctoral researcher to join our team to investigate novel methods to degrade centrosome clustering proteins in cancer cells.

This is a 24-month fixed-term position in the first instance, with the possibility for extension. The project is funded by a North West Cancer Research Cancer Discovery grant, jointly awarded to Dr Morgan Gadd and Dr Andrew Fielding in the Division of Biomedical and Life Sciences at Lancaster University, UK. It is titled “Small molecule induced degradation of centrosome clustering proteins: development of a novel, cancer-specific therapeutic approach.”

You will utilise cutting-edge genetics and chemical biology methods in order to target key centrosome clustering proteins. In particular you will be responsible for designing proteolysis-targeting chimaeras (PROTACs) that will cause degradation of their protein target. These developments will lead to a greater understanding of how targeting these proteins are relevant to the biology of cancers of prominence in the North West, as well as provide the first steps towards discovering therapeutically relevant degraders for our promising targets.

Candidate requirements:

  • A PhD awarded (or soon to be awarded) in a relevant field.
  • A strong background in chemical biology and/or molecular and cell biology.
  • Some experience in synthetic or medicinal chemistry.
  • Experience with mammalian cell culture, plasmid design and CRISPR.
  • An interest in targeted protein degradation and/or cancer drug discovery would be advantageous.
  • Ability to solve problems creatively and plan and work independently, but also work in and/or manage a team when required.
  • Excellent communication and presentation skills, both for communicating within the scientific community and to various audiences in the community as a part of outreach activities.

Our labs in the Division of Biomedical and Life Sciences constitute part of a large and vibrant cancer research grouping. The division is a friendly research environment that strongly supports the individual needs of each employee and which actively promotes a healthy work-life balance.

The Faculty of Health and Medicine is committed to family-friendly and flexible working policies. For example, we are willing to consider flexible or condensed hours for this post. The Faculty has held a Silver Athena SWAN award since 2014 in recognition of its good employment practice undertaken to address gender equality in higher education and research.

In 2018, Lancaster University was named University of the Year by The Times and The Sunday Times Good University Guide whilst recently, in the 2020 guide, has been named International University of the Year.

Informal enquiries are welcome and encouraged.

Please contact: Dr Morgan Gadd (m.gadd@lancaster.ac.uk ), Dr Andrew Fielding (a.fielding1@lancaster.ac.uk) or Dr Sarah Allinson (s.allinson@lancaster.ac.uk) for more information.

We welcome applications from people in all diversity groups.

For further information and to apply online please click the apply button.      

Lancaster University - ensuring equality of opportunity and celebrating diversity.

Company

Student Wellbeing Services are looking for a highly motivated and organised person for the role of Digital Transition Officer within the Transitions team.  

You will contribute to the digital development and co-ordination of a broad package of pre- and post-entry student support programmes, events and services.  Support will be focused on improving the transition to University and the student experience of specific Widening Participation (WP) groups including disabled students and mature students.  You will need experience of developing on-line training or support, and of developing and designing attractive web content.  You will need the ability to work independently as well as the skills to collaborate with colleagues to develop effective schemes and services.You should have experience of collection and analysing data, as well as excellent organisation and problem solving skills and the ability to work to tight deadlines.  

You will need to be able to communicate and work with a wide variety of people including students, staff, parents, external organisations and colleagues within Student and Education Services. You should have experience of preparing written reports and the ability to present evaluation data in a meaningful way for a variety of audiences. Knowledge and understanding of disability would be an advantage.  Occasionally working out of normal office hours including evening and weekends will be required.     

Please note: previous applicants need not apply.

This is a fixed-term, full-time post until the end of July 2020 (with the possibility of further extension). 

We welcome applications from people in all diversity groups.

Company info
Mini-site
LANCASTER UNIVERSITY
Telephone
+(44)0152465201
Location
BAILRIGG
LANCASTER
LANCASHIRE
LA1 4YW
GB

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