Job Description

The Tan lab is looking for a research assistant who will work with Assistant Professor Tan Yong Zi on biochemistry and structural biology under a project entitled Understanding the Structure and Function of Mammalian Membrane Proteins Involved in Human Diseases.

While membrane proteins only make up around 20% of the proteome, they constitute around 60% of drug targets. However, high resolution structural information is severely lacking for them, with only about 2% of the structures deposited in the public protein database (PDB) being annotated as membrane proteins. The Tan lab (www.tyzlab.com) strives to fill in this gap by targeting membrane proteins involved in human diseases such as cancer and diabetes. Our forte is using state-of-the-art single-particle cryogenic electron microscopy (cryo-EM) to obtain high-resolution atomic structures of these membrane proteins. We also actively work on methods development in cryo-EM that will help us answer our biological questions.

The Tan lab is generously funded by the NUS Presidential Young Professorship under the Department of Biological Sciences, NUS. We are a core member of the Centre for BioImaging Sciences' (CBIS), and have access to high-end cryo-EM microscopes, including a Titan Krios with K3 direct detector and energy filter

Main Responsibilities

• Administrative duties of goods ordering, order processing and lab stock keeping
• Involved in maintenance of lab safety and liaison with institute safety team
• Can either be involved in wet lab work or aid in the running of the cryogenic electron microscopes and sample preparation

Application Requirements

• Candidates must uphold values of scientific integrity, honesty, teamwork and pride in their work
• Undergraduate degree or polytechnic diploma both welcomed
• Experience in biochemistry, molecular biology, cell culture work or electron microscopy would be a plus but not necessary
• Few years of work experience would be a plus but not necessary

Interested candidates please contact Dr. Tan Yong Zi at yztan(at)nus.edu.sg. Please provide a CV and names and contact of three referees.

At NUS, the health and safety of our staff and students is one of our utmost priorities and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require significant amount of physical interactions with student / staff / public members. Even for job roles that can be performed remotely, there will be instances where on-campus presence is required. 

With effect from 15 January 2022, based on Singapore’s legal requirements, unvaccinated workers will not be able work at the NUS premises. As such, we regret to inform that job applicants need to be fully COVID-19 vaccinated for successful employment with NUS. 

MOM Updated Advisory on COVID-vaccination at the Workplace, subject to changes in accordance with the national COVID-19 measures.

Qualification

Application Requirements

• Candidates must uphold values of scientific integrity, honesty, teamwork and pride in their work
• Undergraduate degree or polytechnic diploma both welcomed
• Experience in biochemistry, molecular biology, cell culture work or electron microscopy would be a plus but not necessary
• Few years of work experience would be a plus but not necessary

More Information

Location: [[Kent Ridge]]
Organization: [[National University of Singapore]]
Department : [[Department of Biological Sciences]]
Employee Referral Eligible: [[No]]
Job requisition ID : 11679