CRUK ECRIN-M3 Senior Data Manager

Southampton, United Kingdom
Monday, 7 June 2021
End of advertisement period
Friday, 2 July 2021
Contract Type
Fixed Term
Full Time

Cancer Sciences

Location:  Southampton General Hospital
Salary:   £39,152
Full Time Fixed Term (until 31/08/2025)
Closing Date:  Friday 02 July 2021
Interview Date:   To be confirmed
Reference:  1384921CM

Applications are invited for a CRUK Senior Data Manager position to join the CRUK accelerator programme ‘Early Cancer Research Initiative Network on Monoclonal B-cell Lymphocytosis (ECRIN-M3) awarded to Professor Francesco Forconi.

For personalised medicine to become a clinical reality, we must meaningfully collate, integrate and interrogate patient multi-dimensional data. You will deliver a learning health system in which clinical and routine diagnostic and research laboratory data are integrated and interrogated to discover new prognostic signatures and refine the risk stratification of cancer patients from the very early stages.

You will lead on the data management of the programme to ultimately stratify prognostic risk of patients with B-cell cancers, including monoclonal B-cell lymphocytosis (MBL, >10% of individuals older than 40 years in the general population), and chronic lymphocytic leukaemia (CLL, the most common leukaemia in the Western world).

Working with data specialists and an expanding team of clinicians and scientists with a firm grounding in cancer B-cell immunology, genomics, molecular/cellular biology across the Cancer B-cell group and the Clinical Informatics Research Unit (CIRU), you will be responsible for populating and integrating medical, molecular and functional data from a very large cohort of patients in the recruiting local and international sites of the ECRIN-M3 programme. You will use the Electronic Case Report Form ALEA and BC Platforms data warehouse and ensure the collection and validation of the data flowing from recruiting sites into your platforms.

You will be curious, enthusiastic, and well-motivated to develop your research, and a good team player with excellent data management and communication skills. You will be expected to deliver high-impact publications, contributing to the international reputation of the Cancer B-cell Group.

The successful candidate will have a PhD degree or equivalent professional qualification and experience, with deep knowledge of data acquisition and medical statistics and/or epidemiology. Knowledge of prognostic scores in mature B-cell malignancies, including chronic lymphocytic leukaemia, is desirable. Applications from EU and international candidates are welcome. This post will be based at the Cancer Research UK Centre and Centre for Cancer Immunology within the School of Cancer Sciences at the Southampton General Hospital campus, occupying modern, well-equipped, purpose-built laboratories, with support from clinical and laboratory-based colleagues.

Additional details about the School of Cancer Sciences can be found at

The position is funded by Cancer Research UK and is full-time, fixed-term to 31st August 2025 in the first instance, subject to continued funding. For an informal discussion or to arrange a visit, please contact Professor Francesco Forconi ( or Professor James Batchelor ( 

Application Procedure 

You should submit your completed online application form at The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Annabelle Trimm (Recruitment Team) on +44 (0) 23 8059 4043 or email  Please quote reference 1384921CM on all correspondence.