CRUK ECRIN-M3 Data Manager/Scientist in B-Cell Malignancies
Location: Southampton General Hospital
Salary: £30,942 to £33,797 per annum
Full Time Fixed Term until 31/08/2025
Closing Date: Sunday 18 April 2021
Interview Date: To be confirmed
Applications are invited for a CRUK Data Scientist/Manager position to join the CRUK accelerator programme ‘Early Cancer Research Initiative Network on Monoclonal B-cell Lymphocytosis (ECRIN-M3)' awarded to Professor Francesco Forconi.
For personalised medicine to become a clinical reality we must meaningfully integrate and interrogate patient multi-dimensional data. We can produce a learning health system in which high dimensional data is routinely integrated into the clinical arena and iteratively interrogated to discover new prognostic and stratification signatures and refine those known.
You will lead in a new clinical research study on the management of the clinical and research data of monoclonal B-cell lymphocytosis (MBL) and other early-stage B cell malignancies, working with data specialists in the Clinical Informatics Research unit (CIRU) and with an expanding team of clinicians and scientists with a strong grounding in cancer B-cell immunology, genomics, molecular/cellular biology and bioinformatics at the School of Cancer Sciences. You will use an Electronic Case Report Form ALEAS and the BC Platforms data warehouse incorporating medical records and high-dimensional biomedical data, as well as applying the latest trans-disciplinary data analysis techniques to refine phenotypic, genetic and functional marker to improve clinical decision-making. You will ensure the collection and validation of clinical and biological data flowing from recruiting sites into your platforms. You will coordinate the study by interacting directly with local ECRIN-M3 team members, research assistants and nurses, and with international collaborators, including those from Spain and Italy involved in the programme.
You will be an enthusiastic and well-motivated investigator capable of developing your research project as well as a good team-player with excellent data management and communication skills, working in a fertilising environment of clinicians and scientists with a strong grounding in cancer B-cell immunology, genomics, molecular/cellular biology and bioinformatics. You will design new models of disease progression from the very early stages (early cancer) to overt B-cell leukaemias and lymphomas. You will be expected to contribute to the development and enhancement of the B-cell group within the School of Cancer Sciences, nationally and internationally.
The successful candidate will have a PhD degree or equivalent EU qualification and experience, with deep knowledge of medical statistics and/or epidemiology. Knowledge on prognostic scores in mature B-cell malignancies, including chronic lymphocytic leukaemia and indolent B-cell lymphomas are desirable. Applications from EU and international candidates are welcome.
This post will be based within the Cancer Research UK Centre and Centre for Cancer Immunology at the Southampton General Hospital campus, occupying modern, well-equipped, purpose-built laboratories, with support from clinical and laboratory-based colleagues.
Additional details about the School of Cancer Sciences can be found at https://www.southampton.ac.uk/medicine/academic_units/academic_units/cancer_sciences.page
The position is funded by Cancer Research UK and is full-time, fixed-term to 31 August 2025 in the first instance, subject to continued funding . For an informal discussion or to arrange a visit, please contact Professor Francesco Forconi (firstname.lastname@example.org) or Professor James Batchelor (J.Batchelor@soton.ac.uk).
Submit your completed online application form at www.jobs.southampton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Kate Pounds on +44 (0) 23 8059 2507. Please quote reference 1348821CM on all correspondence.
The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.