Postdoctoral Associate, Schwartz Lab

Massachusetts, United States
Wednesday, 10 February 2021
End of advertisement period
Saturday, 10 April 2021
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Full Time

Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.

POSTDOCTORAL ASSOCIATEBiology (2 openings), to study nucleo-cytoplasmic communication in the Schwartz Lab.  Recent references include:  Nordeen et al., Nat Comm 2020, Nordeen et al., Nat Comm 2020, Lim et al., bioRxiv 2020.  Will work on federally funded projects elucidating structure and function of nucleo-cytoplasmic communication.  One project involves the structure of the nuclear pore complex (NPC), with the goal of reducing the resolution gap between crystal structures of NPC components and cryo-ET assembly structures. The lab works at the interface of bioengineering and structural biology to solve this problem with innovative methods.  The second project centers on the mechanical connections between nucleo- and cytoskeleton via LINC complexes. Here, the lab wants to understand the details for LINC complex engagement, in particular, with the lamin layer and with actin filaments. For both projects, the lab has a vast array of reagents, tools, and expertise to build on. MIT also has a brand-new, state-of-the-art, fully-staffed cryo-EM facility equipped with a Talos Arctica and a Titan Krios with energy filter and phase plate. Both instruments have direct detectors. There is also ample access to two cryo-FIB mills on campus.

Job Requirements

REQUIRED: a Ph.D. in the life sciences that includes a significant cryo-EM component, self-motivation, and a strong desire to work in structural cell biology. Job #19151

Interested candidates should submit names of three references with their application material.

This is a one-year, renewable position based upon available funding and research priorities.