Research Nurse Practitioner

Pennsylvania, United States
Tuesday, 9 February 2021
End of advertisement period
Saturday, 10 April 2021
Contract Type
Full Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Profile Title

Advanced Practice Nurse

Job Description Summary

Research APP will see the research patient, write notes, do toxicity grading/attribution, place orders, observe patients during infusion
They are on 1572s, so function as Sub-Is and are trained intensively on protocols. Between patient visits, they also manage all the research patient phone calls, arrange bx etc.

  • The biggest advantages to have NPs are (1) their ability to prescribe and (2) their ability to see patients independently
  • They will serve as a resource to the lead nurse and PM to create beacon protocols, AE attribution, management of adverse events
  • We anticipate to start the Research APP with 2-3 protocols, with a goal to see about 10-15 research visits a week.
  • This research APP will live on the APP side, but will have dual reporting to Hem Onc and within ACC.

Job Description

  • Advanced Practice Nurse will work independently with minimal supervision. May act in a lead capacity or as back‐up to the supervisor.
  • Work directly with physicians to design, set-up and execute clinical trials. May be required to speak at investigator meetings or site initiation visits for investigator-initiated trials (“IITs”) where physician is the national PI. Assist in analyzing data to determine response and clinical outcomes; assist with literature reviews; contribute to preparation of study abstracts, posters, manuscripts and grant applications.
  • Collaborate with designated physicians and research team members (consisting of principal investigators, clinical research nurses, clinical research coordinators and clinical research assistants).
  • Clinical responsibilities include conducting a history and physical exam, monitoring toxicities, assessing clinical responses and providing exemplary patient care while ensuring the protocol is conducted in a high quality manner. Monitoring toxicities, assessing clinical status and providing direct patient care while insuring the protocol is conducted in a high quality fashion.
  • Clinical responsibilities include being available during protocol directed infusion therapy as indicated or necessary depending on the circumstance.
  • Clinical responsibilities include management of phone calls/ messages from enrolled clinical trial patients, and working closely with the PI, MD, and nurses to deliver exceptional care.
  • Work in collaboration with unit managers with initiating study procedures for new IITs and industry-sponsored clinical trials. Manage all aspects of Phase I – IV clinical trials. Participate in the conduct of audits by study sponsors, CROs, the FDA, the Eastern Oncology Group, the University of Pennsylvania’s CTSRMC, and other groups.
  • Develop and maintain ongoing communication with the clinical teams including, but not limited to: laboratory, infusion, radiology, Advanced Practitioners, triage, inpatient, bed management, beacon hybrid, and pharmacy. Provide support to infusion, CHPS or inpatient staff as appropriate. Provide ongoing service education updates to all investigators and HUP staff that have eligible participants for clinical research trials.
  • Screening patients for protocols and participating in the informed consent process and providing education for patients considering enrollment.
  • Review clinical/laboratory data and adverse events, manage protocol-specific toxicities in collaboration with the principal investigator and research team.
  • Handle any questions subjects may have regarding protocol specifics, investigational products, lab results, effects of therapies, medications, and symptom management within level of expertise and referring other questions to the PI or medical team in order to obtain guidance or assistance.
  • Remain knowledgeable about protocol and protocol amendments including dose modifications and adjustments.
  • If needed, collect, review, provide guidance, and report timely, valid, accurate study data within the timelines specified by the Clinical Trials Agreement. Coordination may also include: transporting specimens, submission of study documents to all applicable institutional committees (e.g., IRB, CTSRMC, IBC, CTRC) for initial approval, continuing reviews and for approval of any amendments.
  • Represents the disease‐site team when meeting with Medical Science Liaisons, current and future research collaborators, and prospective donors; assists physician and unit manager in coordinating development plans. Participation in national meetings, as well as University department meetings and committees.


Master's degree in Nursing with 5 to 7 years of experience or an equivalent combination of education and experience required.   Graduate of a NLN- approved school of nursing. RN and CRNP licensure in the State of Pennsylvania. Completion of an approved Nurse Practitioner program with a MSN is required. Must have current CPR certification. Prior 5-7 years of nursing experience in specialty is preferable. This position is Monday through Friday. 40 hours per week Hours may be adjusted to meet the operational needs of the department.

The position is contingent upon funding.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$59,703.00 - $113,435.00

Affirmative Action Statement 

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job