Life Science Research Professional 1

Location
California, United States
Posted
Monday, 8 February 2021
End of advertisement period
Friday, 9 April 2021
Ref
88341
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

The laboratory of Dr. Inma Cobos at Stanford University is seeking a Life Science Research Professional 1 to study Alzheimer’s disease and related neurodegenerative dementias.

About the laboratory of Dr. Inma Cobos:

The focus of our lab is to understand Alzheimer’s disease and related neurodegenerative dementias at the single-cell level. We apply innovative technologies such as single-cell RNA-sequencing and spatial transcriptomics to human brain to understand the contributions of individual cell types to disease pathogenesis. Our lab provides an ideal opportunity for outstanding staff and trainees to advance their careers by joining a highly collaborative team of scientists, physicians and computational biologists working across disciplines to accelerate progress in neurodegeneration.

About the Department of Pathology:

Comprised of extraordinary faculty and staff, our mission is to improve the diagnosis, treatment and basic understanding of human disease. We accomplish this through our clinical services, research, and training the future leaders in pathology and related fields.  A major focus of research in the Department is to innovate and assure Stanford’ pre-eminence in clinical diagnostics and prognostic testing molecular medicine.  Everything we do is to provide the highest quality of pathology diagnostic services to the patients for whom we passionately care.

For more information about the department visit http://pathology.stanford.edu/ 

Duties include:

  • Support lab research projects including single-cell transcriptome profiling of human brain with neurodegenerative disease and mouse models of dementia.
  • Independently conduct experiments including histological analysis of human and mouse brain tissue (i.e., multiplex immunohistochemistry and mRNA in situ hybridization); acquire and analyze microscopy images; maintain detailed records of experiments and outcomes.
  • Analyze and interpret experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researchers.
  • Review literature to remain current with new procedures and apply knowledge to ongoing projects.
  • Contribute to publication of findings as needed. Participate in the preparation of written documents including procedures, presentations and proposals.
  • Help with general lab maintenance as needed including maintaining lab stocks and managing chemical inventory and safety records; help maintaining mouse colonies; growing and maintaining cell lines; provide general lab support as needed.
  • Assist with orientation and training of new staff or students on lab procedures or techniques.

*- Other duties may also be assigned

Desired Qualifications:

  • Bachelor’s degree in Biological Sciences, Cell Biology, Genetics or related field.
  • Experience and knowledge of planning, performing, and interpreting the following:
  • Brain human or mouse tissue processing (sectioning and staining)
  • Immunohistochemistry and mRNA in situ hybridization  
  • Immuno-assays (ELISA, western-blot)
  • Cell and tissue in vitro culture
  • Basic molecular biology techniques
  • Handling mouse colonies (breeding, genotyping)
  • Fluorescence and brightfield microscopy
  • The candidate should be able to work independently, be highly motivated, adaptable and work well within a highly interdisciplinary and international team. 
  • Good communication and interpersonal skills
  • Proficient computer skills

Education & Experience (REQUIRED):

Bachelor's degree in related scientific field.

Knowledge, Skills and Abilities (REQUIRED):

Physical Requirments*:

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Working Conditions:

  • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
  • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
  • Ability to maintain detailed records of experiments and outcomes.
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
  • Ability to work under deadlines with general guidance.
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.
  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
  • Must have correctible vision to perform duties of the job.
  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
  • Ability to lift heavy objects weighing up to 50 pounds.
  • Ability to work in a dusty, dirty, and odorous environment.
  • Position may require repetitive motion.
  • May require working in close proximity to blood borne pathogens.
  • May require work in an environment where animals (mice) are used for research.
  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves.
  • May require extended or unusual work hours based on research needs.

Additional Information

  • Schedule: Full-time
  • Job Code: 4945
  • Employee Status: Regular
  • Grade: E
  • Requisition ID: 88341
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