KINGS COLLEGE LONDON

Research Associate

Location
London (Greater) (GB)
Salary
£38,304 - £41,517 per annum, including London Weighting Allowance
Posted
Wednesday, 23 September 2020
End of advertisement period
Thursday, 22 October 2020
Ref
R6/1203/20-RL
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Hours
Full Time

This position is for a talented and enthusiastic postdoctoral molecular/cell biologist or physiologist to work on a BHF Programme Grant on Redox-regulated adaptive pathways in heart failure. The project will involve the use of iPSC-derived cardiomyocytes and “engineered heart muscle (EHM)” as model systems to investigate biological mechanisms. We therefore seek to appoint an individual with a strong background in cell and molecular biology (rather than tissue engineering), e.g.cloning, viral transduction, CrispR/Cas9 approaches, immunoblotting, microscopy of tissue sections. Previous experience with iPSC-derived cardiomyocytes or EHM is highly desirable. Experience with muscle force measurements and/or the use of in vivo models of disease would be helpful.

The postholder will be part of a multi-disciplinary research grouping working on several different aspects of cardiovascular pathophysiology, with access to state-of-the-art laboratory facilities within the King’s BHF Centre of Research Excellence.

Key responsibilities

  • Develop and undertake research of high quality consistent with making a full active research contribution in line Department/Division/School research strategy
  • Manage specific pieces of activity to an agreed timeline and within a specific budget including literature reviews, data collection and analysis, report writing.
  • Attend and, as appropriate, present research findings and papers at internal academic meetings and external professional conferences, and to contribute to the internal and external visibility of the department.
  • Work as a conscientious and committed member of the team in order to achieve the aims of the projects and the primary care group.
  • Facilitate collaboration and networking which engages and supports the activities of the project
  • Participate in educational activities as appropriate to the stage of your career.
  • To be committed to your own personal career development.
  • Liaise with the administrative team for the support of the project
  • Contribute to publications arising from this project
  • Undertake any other reasonable duties that may be relevant to the role outline.

Communication & Networking:

  • Deal with routine communication using a range of media
  • Communicate complex information orally and in writing
  • Communicate material of a specialist or highly technical nature
  • Liaise with colleagues and students
  • Build internal contacts and participate in internal networks for the exchange of information and to form relationships for future collaboration
  • Join external networks to share information and identify potential sources of funds

Decision Making, Planning and Problem Solving:

  • Use new research techniques and methods
  • Identify areas for research, develop new research methods and extend the research portfolio
  • Contribute to collaborative decision making with colleagues in area of research

Service Delivery:

  • Respond to requests for information in accordance with College policies
  • Provide advice with respect to own areas of expertise
  • Set the standards of service and ensure overall quality is maintained

Analysis & Research:

  • Develop research objectives and proposals for own or joint research, with the assistance of a mentor
  • Conduct individual and collaborative research projects
  • Write up research work for publication
  • Maintain knowledge, expertise and awareness of relevant research literature by self-directed enquiry and continuing education
  • Translate knowledge of advances in the area of expertise into research activity
  • Analyse and interpret research data and draw conclusions on the outcomes

Teamwork, Teaching & Learning Support:

  • Work with colleagues on joint projects as required
  • Collaborate with academic colleagues on areas of shared research interest
  • Attend and contribute to relevant meetings
  • Contribution to the supervision or training of more junior staff and students as necessary
  • Contribution to laboratory maintenance and administration.

Pastoral Care:

  • Show consideration to others

Skills, knowledge, and experience

Essential criteria

  • PhD in a relevant biological sciences project
  • Strong background in cell/molecular biology
  • Good written presentation skills, communication skills (written & verbal), and good IT skills
  • Broad molecular biology research experience (e.g. cloning, RT-PCR)
  • Broad cell biology experience, e.g. immunoblotting, primary cell culture, confocal microscopy, immunofluorescence
  • Successful completion of research projects (published papers in high Impact Factor journals)
  • Self-motivated, able to work independently, as well as willing and able to work as part of a team
  • Commitment to continuing personal and professional development,
  • Able to carry out know/learnt techniques unsupervised, and flexible/able to change in current professional context
  • Able to plan and prioritise workload and keep clear and well-organised laboratory notes and records

Desirable criteria

  • Background in cardiovascular biology
  • Experience of working with iPS-derived cardiomyocytes or engineered heart muscle
  • Experience of working with in-vivo models of disease or gene-modification

This advertisement does meet the requirements for a Certificate of Sponsorship under Home Office regulations and therefore the university will be able to offer sponsorship for this role.

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