KINGS COLLEGE LONDON

Research Assistant

Location
London (Greater) (GB)
Salary
Grade 5, £32,160 per annum, inclusive of £3,500 per annum London Allowance
Posted
Monday, 9 September 2019
End of advertisement period
Wednesday, 9 October 2019
Ref
R5/1979/19-DB
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Hours
Full Time

We are inviting applications for a Research Assistant who will conduct lipid analyses and will use imaging, RNAi, CRISPR and small molecule treatment to analyse cultured cells as disease models. This will require excellent knowledge in the techniques indicated below.

 The role holder will investigate the basic cell biology of LSDs, with an initial focus on Gaucher, which is caused by a mutation in the enzyme GBA.  The lysosomal storage disorders (LSDs) are inherited rare diseases where key lipid metabolic enzymes are mutated, resulting in the inappropriate accumulation of some lipid species.  Many LSDs result in progressive neurodegeneration, as well as numerous other symptoms.  There has been clinical success in treating more common LSDs such as Gaucher.  However, unfortunately, there are no therapies for most LSDs and there remain considerable challenges in their diagnosis and treatment.

The selection process will include a panel interview.

To apply, please register with the King’s College London application portal and complete your application online.

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